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KMID : 0363420010150010131
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Journal of Korean Oriental Pediatrics
2001 Volume.15 No. 1 p.131 ~ p.153
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Effect of Kami-Hyunggyeyungyotang on Immunoglobulin-G Subtypes in Middle Ear Effusion for Pediatric Recurrent Otitis Media with Effusion
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Abstract
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The author measured IgG1, IgG2, IgG3 and IgG4 levels of 22 ears-11 ears of them had treated by antibiotics, 11 of them by Kami-hyunggyeyungyotang-of pediatric recurrent otitis media with effusion using ELISA assay, and compared them. The results were obtained as follows. 1. The level of IgG1 in Kami-hyunggyeyungyotang group was significantly higher than that in antibiotics group(P=0.002). 2. The level of IgG2 in Kami-hyunggyeyungyotang group was higher than that in antibiotics group(P=0.178). 3. The level of IgG3 in Kami-hyunggyeyungyotang group was higher than that in antibiotics group(P=0.215). 4. The level of IgG4 in Kami-hyunggyeyungyotang group was higher than that in antibiotics group(P=0.198). According to above results, Kami-hyunggyeyungyotang is considered to be used for treatment ’’recurrent otitis media with effusion’’ by controlling the production of immunoglobulins.
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